What Profhilo Actually Does
Profhilo is an injectable treatment made from a very high concentration of hyaluronic acid. It is not a filler. It does not add volume, and it does not change the structure of your face. What it does is spread through the skin and hydrate it deeply from within.
Here is what happens after treatment:
The hyaluronic acid draws and holds water in the skin, plumping it from the inside. This gives the skin a smoother, dewier appearance.
Well-hydrated skin reflects light better. Most clients notice their skin looks brighter and more alive within a few weeks.
Profhilo stimulates some collagen and elastin production. This is gentle, not dramatic, but it helps improve skin tone and elasticity over time.
I use Profhilo regularly at my Fulham clinic and it is a brilliant treatment when matched to the right person. The key word there is "right person."
Results Timeline: What to Expect
Profhilo is a two-session treatment. The second session happens four weeks after the first. Results build gradually. Here is what my clients in London typically experience:
The injection bumps settle within hours. Over the first couple of weeks, the hyaluronic acid starts integrating into the skin. Some people notice a subtle improvement in how their skin feels, but visible changes are usually minimal at this stage. The second session happens at the four-week mark.
This is when things come together. After both sessions, the skin starts to look noticeably more hydrated, brighter, and smoother. Fine lines look softer. Skin tone is more even. This is the point where most people look in the mirror and think, "that has actually worked."
Watch a Profhilo Treatment
Why Some People Think Profhilo Does Not Work
I hear this fairly often. Someone has had Profhilo and they feel like it did not do much. In almost every case, the reason comes down to one of three things:
Wrong candidate
If your skin has significant laxity, deep wrinkles, or volume loss, Profhilo is not going to address those concerns. It hydrates and refreshes. It does not lift, fill, or structurally rebuild. When someone with advanced skin ageing has Profhilo alone, they are often disappointed because the treatment was never designed to solve that problem.
Skin too damaged for hydration alone
Some skin needs more than moisture. If your skin is thin, crepey, or has been through years of sun exposure, the structural integrity is compromised. Hydration helps, but it cannot repair what has been lost. This is where treatments like polynucleotides are more appropriate because they actually regenerate tissue.
Needed a combination approach
For many clients, the best outcome comes from combining Profhilo with another treatment. Profhilo handles the hydration and glow. Polynucleotides handle the repair and regeneration. Together, they cover more ground than either treatment alone.
Who Profhilo Is (and Is Not) For
Works Well For
- +Dull, tired-looking skin that has lost its glow
- +Dehydrated skin that feels dry despite good skincare
- +Early signs of ageing with fine lines forming
- +Pre-event skin prep when you want to look refreshed
- +Maintenance between more intensive treatments
Not Enough On Its Own For
- xCrepey or paper-thin skin that needs regeneration
- xSignificant skin laxity or sagging
- xDeep wrinkles or structural volume loss
- xUnder-eye hollowing or dark circles
- xAcne scarring or textural damage
The Honest Way I Explain It to Clients
If your skin looks dull or tired but is not damaged, Profhilo works really well. You will notice a genuine improvement in how your skin looks and feels. It is one of the best treatments available for that "I just look a bit flat" feeling.
But if your skin is thinner, more crepey, or has lost its firmness, this is where people feel like Profhilo has not worked. It is not that the treatment failed. It is that the skin needed something different, or something more.
That is why I always do a proper assessment at my Fulham clinic before recommending anything. Sometimes Profhilo is exactly the right call. Sometimes polynucleotides are a better fit. And sometimes a combination of both gives the best result.
How Profhilo Compares
| Profhilo | Polynucleotides | Botox | |
|---|---|---|---|
| Primary goal | Hydration & glow | Skin regeneration | Wrinkle relaxation |
| How it works | Bio-remodelling | Cellular repair | Muscle relaxation |
| Best for | Dull, dehydrated skin | Damaged, thin skin | Expression lines |
| Results speed | 2 to 6 weeks | 6 to 12 weeks | 3 to 7 days |
| Lasts | About 6 months | 6 to 12 months | 3 to 4 months |
| Under-eye use | Limited | Excellent | No |
| Depth of change | Surface hydration | Deep regeneration | Muscle only |
Want to Know If Profhilo Is Right for Your Skin?
The only way to know for sure is a proper skin assessment. I will look at your skin, understand your goals, and tell you honestly whether Profhilo, polynucleotides, or a combination would give you the best result.
Book a ConsultationFulham, London. In-person consultations available.
Complimentary Red Light Therapy
Included at no additional cost with qualifying skin treatments.
All regenerative skin treatments at Georgina Sookias Aesthetics include complimentary professional Red Light Therapy.
Our professional system combines 630nm and 660nm red light with 810nm, 830nm and 850nm near infrared wavelengths. These wavelengths have been widely studied for their ability to support skin health, cellular energy production and collagen synthesis.
As part of our regenerative approach to skin health, we include professional Red Light Therapy after qualifying treatments to support the skin during the recovery phase and enhance the overall treatment experience at no additional cost.
This is provided complimentary with all qualifying skin treatments as part of our regenerative approach to skin health.
Frequently Asked Questions
Does Profhilo really work?
Yes, but for the right person. Profhilo works best on skin that is dehydrated, dull, or showing early signs of ageing. It hydrates from within and stimulates mild collagen production. It is not designed for skin that is significantly damaged, crepey, or has lost structural support.
How long does it take to see Profhilo results?
Most clients notice a visible improvement in skin hydration and glow within two to four weeks after the second session. Full results, including improved elasticity and smoother texture, typically develop over four to six weeks.
Why do some people say Profhilo did not work for them?
The most common reason is that Profhilo was not the right treatment for their skin concern. Profhilo is a hydration and glow treatment. If someone has crepey skin, volume loss, or significant laxity, they need a different approach such as polynucleotides, filler, or a combination plan.
How many Profhilo sessions do you need?
The standard protocol is two sessions spaced four weeks apart. Some clients benefit from a third session depending on their skin condition. Maintenance is typically recommended every four to six months.
Is Profhilo worth it for older skin?
Profhilo can be part of a treatment plan for older skin, but it is rarely enough on its own. For skin that has lost significant firmness or elasticity, combining Profhilo with polynucleotides or other regenerative treatments tends to produce much better results.